Olodaterol hydrochloride
Cat. No.：YN322673
CAS No. ：869477-96-3
| 产品名称: | Olodaterol hydrochloride |
| CAS No.: | 869477-96-3 |
| Chemical Name: | 6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one Hydrochloride; BI 1744 Hydrochloride |
| Synonyms: | BI1744 hydrochloride |
| 分子量: | 422.9 |
| 分子式: | C21H27ClN2O5 |
| SMILES: | CC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Olodaterol (BI1744) hydrochloride 是一种选择性、长效的β2-adrenoceptor(β2-AR) 激动剂 (EC50=0.1 nM；pKi= 9.14 for human β2-adrenoceptor)。 Olodaterol hydrochloride 可用于慢性阻塞性肺疾病 (COPD) 和肺纤维化。 |
| IC50和靶点: | [{name:"β2 adrenoceptor:.1 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Cazzola, M., et al.: Pharmacol. Rev., 64, 450 (2012)
Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010)
