Trabodenoson
Cat. No.：YN322675
| 产品名称: | Trabodenoson |
| CAS No.: | 871108-05-3 |
| Chemical Name: | N-cyclopentyl-adenosine, 5′-nitrate |
| Synonyms: | INO-8875 |
| 分子量: | 380.35614 |
| 分子式: | C15H20N6O6 |
| SMILES: | O[C@H]1[C@](O[C@@H]([C@H]1O)CO[N+]([O-])=O)([H])N2C3=NC=NC(NC4CCCC4)=C3N=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trabodenoson (INO-8875) 是一种腺苷模拟物，是高选择性的腺苷 A1 受体 (Adenosine A1 receptor) 的激动剂。Trabodenoson (INO-8875) 可用于原发性开角型青光眼的研究。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Mor, M., Shalev, A., Dror, S., et al.INO-8875, a highly selective A1 adenosine receptor agonist: Evaluation of chronotropic, dromotropic, and hemodynamic effects in ratsJ. Pharmacol. Exp. Ther.344(1),59-67(2012)
Kim, N., Crosson, C., Supuran, C., et al.INO-8875, an adenosine A1 agonist, in development for open-angle glaucoma reduces IOP in three rabbit modelsInvert. Ophthalmol. Vis. Sci.50(13),4061(2009)
