PSNCBAM-1
Cat. No.：YN322680
| 产品名称: | PSNCBAM-1 |
| CAS No.: | 877202-74-9 |
| Chemical Name: | N-(4-chlorophenyl)-N'-[3-[6-(1-pyrrolidinyl)-2-pyridinyl]phenyl]-urea |
| Synonyms: | PSNCBAM-1; PSNCBAM 1; PSNCBAM1. |
| 分子量: | 392.8812 |
| 分子式: | C22H21ClN4O |
| SMILES: | ClC1=CC=C(NC(NC2=CC(C3=NC(N4CCCC4)=CC=C3)=CC=C2)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PSNCBAM-1 是一种选择性的CB1受体变构拮抗剂，其EC50为 0.1 μM。PSNCBAM-1 可用于肥胖症的研究。 |
| IC50和靶点: | [{name:"hCB1-R:0.1 μM (EC50)"}] |
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Horswill, J.G., Bali, U., Shaaban, S., et al.PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in ratsBr. J. Pharmacol.152(5),805-814(2007)
Gamage, T.F., Farquhar, C.E., Lefever, T.W., et al.The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulatorsNeuropharmacology125,365-375(2017)
