(Rac)-Rotigotine-d
Cat. No.：YN322682
| 产品名称: | (Rac)-Rotigotine-d |
| CAS No.: | 879089-64-2 |
| Chemical Name: | 1,4-dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrolo[3,2-b]pyridin-5-one, dihydrochloride |
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| 分子量: | 288.17252 |
| 分子式: | C12H13N3O • 2HCl |
| SMILES: | O=C1C=CC2=C(N1)C(C3=CCNCC3)=CN2.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CP 93129 dihydrochloride 是一种有效的5HT1B受体激动剂。CP 93129 dihydrochloride 具有帕金森病研究潜力。 |
| IC50和靶点: | |
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Koe, B.K., Nielsen, J.A., Macor, J.E., et al.Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253Drug Dev. Res.26(3),241-250(1992)
Chadha, A., Sur, C., Atack, J., et al.The 5HT1B receptor agonist, CP-93129, inhibits [3H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated ratBr. J. Pharmacol.130(8),1927-1932(2000)
Lee, M.D., Aloyo, V.J., Fluharty, S.J., et al.Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in ratsPsychopharmacology (Berl.)136(3),304-307(1997)
Bannai, M., Fish, E.W., Faccidomo, S., et al.Anti-aggressive effects of agonists at 5-HT1B receptors in the dorsal raphe nucleus of micePsychopharmacology (Berl.)193(2),295-304(2007)
