LY83583
Cat. No.：YN322694
CAS No. ：91300-60-6
| 产品名称: | LY83583 |
| CAS No.: | 91300-60-6 |
| Chemical Name: | 6-(phenylamino)-5,8-quinolinedione |
| Synonyms: | LY83583 |
| 分子量: | 250.3 |
| 分子式: | C15H10N2O2 |
| SMILES: | O=C1C=C(Nc2ccccc2)C(=O)c2cccnc12 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LY83583 是一种可透过细胞膜的可溶性鸟苷酸环化酶 (sGC)竞争性抑制剂，其IC50值为 2 µM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Mülsch, A., Lückhoff, A., Pohl, U., et al.LY 83583 (6-anilino-5,8-quinolinedione) blocks nitrovasodilator-induced cyclic GMP increases and inhibition of platelet activationNaunyn Schmiedebergs Arch. Pharmacol.340,119-125(1989)
Fleisch, J.H., Haisch, K.D., Spaethe, S.M., et al.Pharmacologic analysis of two novel inhibitors of leukotriene (slow reacting substance) releaseJ. Pharmacol. Exp. Ther.229,681-689(1984)
Lüönd, R.M., McKie, J.H., and Douglas, K.T.A direct link between LY83583, a selective repressor of cyclic GMP formation, and glutathione metabolismBiochem. Pharmacol.45,2547-2549(1993)
