Tandospirone hydrochloride
Cat. No.：YN322695
| 产品名称: | Tandospirone hydrochloride |
| CAS No.: | 913612-38-1 |
| Chemical Name: | |
| Synonyms: | OPC-34712 hydrochloride |
| 分子量: | 470.03 |
| 分子式: | C25H28ClN3O2S |
| SMILES: | O=C1NC2=C(C=CC(OCCCCN3CCN(C4=C(C=CS5)C5=CC=C4)CC3)=C2)C=C1.[H]Cl.[x] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brexpiprazole (OPC-34712) hydrochloride，一种非典型的、具有口服活性的抗精神紊乱剂，是人5-HT1A和多巴胺受体（dopamine D2Lreceptor）的部分激动剂，Ki分别为 0.12 nM 和 0.3 nM。Brexpiprazole hydrochloride 也是5-HT2A受体的拮抗剂，Ki为 0.47 nM。Brexpiprazole hydrochloride 对人去甲肾上腺素能受体 α1B(Ki=0.17 nM) 和 α2C(Ki=0.59 nM) |
| IC50和靶点: | [{name:"5-HT1A Receptor:0.12 nM (Ki)"},{name: "5-HT2A Receptor:0.47 nM (Ki)"},{name: "D2L Receptor:0.3 nM (Ki)"},{name: "human noradrenergic α1B:0.17 nM (Ki)"},{name: "human noradrenergic α2C:0.59 nM (Ki)"}] |
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