Clopidogrel-d
Cat. No.:YN322697
产品名称: | Clopidogrel-d |
CAS No.: | 917567-60-3 |
Chemical Name: | 3-(2-Oxo-2-phenylethyl)uridine 5'-(Trihydrogen Diphosphate) |
Synonyms: | |
分子量: | 522.29 |
分子式: | C17H20N2O13P2 |
SMILES: | O[C@H]([C@@H]1O)[C@@](N(C=CC2=O)C(N2CC(C3=CC=CC=C3)=O)=O)([H])O[C@@H]1CO[P](O[P](O)(O)=O)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PSB 0474 (3-phenacyl-UDP) 是一种选择性的、有效的P2Y6受体激动剂,EC50值为 70 nM。PSB 0474 抑制星形胶质细胞和小胶质细胞增殖,增加NO释放。PSB 0474 诱导星形胶质细胞凋亡 (apoptosis)。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
(1) Mitchell, C., et al.: J Pharmacol Exp Ther. 343, 755 (2012) & (2) El-Tayeb, A., et al.: J Med Chem. 49, 7076 (2006)