LUF6283
Cat. No.:YN322704
产品名称: | LUF6283 |
CAS No.: | 92933-48-7 |
Chemical Name: | 5-butyl-1H-pyrazole-3-carboxylic acid |
Synonyms: | LUF6283, LUF-6283, LUF 6283 |
分子量: | 168.2 |
分子式: | C8H12N2O2 |
SMILES: | O=C(O)C1=NNC(CCCC)=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LUF6283 是一种口服有效的HCA(2)部分激动剂,其Ki为 0.55 μM。LUF6283 既能达到烟酸有益的降脂作用,又不会产生皮肤潮红的副作用。 |
IC50和靶点: | |
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Li, Z., Blad, C.C., van der Sluis, R.J., et al.Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in miceBr. J. Pharmacol.167(4),818-825(2012)