Azaphen dihydrochloride monohydrate
Cat. No.：YN380420
| 产品名称: | Azaphen dihydrochloride monohydrate |
| CAS No.: | 977-96-8 |
| Chemical Name: | 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-quinolinium, monoiodide |
| Synonyms: | 1,1'-Diethyl-2,2'-cyanine iodide; Decynium 22; Diethylcyanine iodide; Eastman 7851 |
| 分子量: | 454.4 |
| 分子式: | C23H23N2 • I |
| SMILES: | CCN(C1=CC=CC=C1C=C/2)C2=C\C3=[N+](CC)C4=C(C=CC=C4)C=C3.[I-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pseudoisocyanine (iodide) 是单胺转运体和有机阳离子转运体的泛抑制剂，具有抗抑郁活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Fraser-Spears, R., Krause-Heuer, A.M., Basiouny, M., et al.Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporterEur. J. Pharmacol.842,351-364(2019)
Krause-Heuer, A.M., Fraser-Spears, R., Dobrowolski, J.C., et al.Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22Eur. J. Med. Chem.137,476-487(2017)
Marcinkiewcz, C.A., and Devine, D.P.Modulation of OCT3 expression by stress, and antidepressant-like activity of decynium-22 in an animal model of depressionPharmacol. Biochem. Behav.131,33-41(2015)
