SQ 29548
Cat. No.：YN322721
| 产品名称: | SQ 29548 |
| CAS No.: | 98672-91-4 |
| Chemical Name: | (5Z)-7-[(1S,2R,3R,4R)-3-[[2-[(phenylamino)carbonyl]hydrazinyl]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-heptenoic acid |
| Synonyms: | SQ-29548; SQ 29548; SQ29548. |
| 分子量: | 387.5 |
| 分子式: | C21H29N3O4 |
| SMILES: | OC(=O)CCC/C=C\CC1C2CCC(O2)C1CNNC(=O)Nc1ccccc1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SQ 29548 是高亲和力的放射性配体，是一种选择性血栓素-前列腺素 (TP) 的受体的拮抗剂。 |
| IC50和靶点: | |
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Abramovitz, M., Adam, M., Boie, Y., et al.The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogsBiochim. Biophys. Acta1483(2),285-293(2000)
Ogletree, M.L., Harris, D.N., Greenberg, R., et al.Pharmacological actions of SQ 29,548, a novel selective thromboxane antagonistJ. Pharmacol. Exp. Ther.234,435-441(1985)
Ogletree, M.L., and Allen, G.T.Interspecies differences in thromboxane receptors: Studies with thromboxane receptor antagonists in rat and guinea pig smooth musclesJ. Pharmacol. Exp. Ther.260,789-794(1992)
Fukunaga, M., Makita, N., Roberts, L.J., II, et al.Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cellsAm. J. Physiol.264,C1619-C1624(1993)
