Clazosentan
Cat. No.：YN322755
CAS No. ：180384-56-9
| 产品名称: | Clazosentan |
| CAS No.: | 180384-56-9 |
| Chemical Name: | N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 61-1790; VML 588; |
| Synonyms: | Ro 61-1790; VML 588; AXV-034343 |
| 分子量: | 577.57 |
| 分子式: | C25H23N9O6S |
| SMILES: | O=S(C1=NC=C(C)C=C1)(NC2=NC(C3=CC(C4=NNN=N4)=NC=C3)=NC(OCCO)=C2OC5=CC=CC=C5OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Clazosentan (Ro 61-1790) 是一种选择性的内皮素 A 受体 (ETAreceptor) 拮抗剂。Clazosentan 抑制 ET-1 介导的血管收缩。Clazosentan 可预防脑血管痉挛、血管痉挛相关性脑梗死。 |
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Ikeda, Y., et al.: Neurosurgery, 27, 1 (1990), Armstead, W., et al.: J. Neurosurg., 85, 901 (1996)
Armstead, W., et al.: J. Neurotrauma., 18, 1039 (2001)
Uhlmann, D., et al.: Curr. Opin. Investig. Drugs, 7, 272 (2006)
