Physostigmine hemisulfate
Cat. No.：YN380433
| 产品名称: | Physostigmine hemisulfate |
| CAS No.: | 209394-46-7 |
| Chemical Name: | N-Ethyl-N-methylcarbamic Acid (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-5-yl Ester (2R,3R)-2,3-Dihydroxybutanedioate; TV 3326; |
| Synonyms: | TV-3326 hemitartrate |
| 分子量: | 694.77 |
| 分子式: | C16H20N2O2.1/2C4H6O6 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ladostigil (TV-3326) hemitartrate 是一种口服有效的胆碱酯酶(cholinesterase)和脑选择性单胺氧化酶(MAO)的双重抑制剂，抑制MAO-B和AChE的IC50值分别为 37.1 和 31.8 μM。Ladostigil hemitartrate 具有神经保护，抗氧化和抗炎作用，可用于抑郁症和阿尔茨海默症的研究。 |
| IC50和靶点: | [{name:"MAO-B:37.1 nM (IC50)"},{name: "AChE:31.8 nM (IC50)"}] |
| In Vitro: | |
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| Solvent & Solubility: |
Masubuchi, Y., et al.: J. Pharm. Pharmacol., 48, 925 (1996), Weinstock, M., et al.: Brain Res., 595, 195 (1992), Kitada, Y., et al.: Eur. J. Pharmacol., 72, 145 (1981),
