Sarizotan
Cat. No.：YN322768
CAS No. ：351862-32-3
| 产品名称: | Sarizotan |
| CAS No.: | 351862-32-3 |
| Chemical Name: | |
| Synonyms: | EMD 128130 |
| 分子量: | 暂无 |
| 分子式: | 暂无 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sarizotan (EMD 128130) 是具有口服活性的5-HT1A受体和多巴胺受体的激动剂，其IC50值分别为 6.5 nM (rat 5-HT1A)、 0.1 nM (human 5-HT1A)、15.1 nM (rat D2)、17 nM (human D2)、6.8 nM (human D3) 和 2.4 nM (human D4.2)。 |
| IC50和靶点: | [{name:"5-HT1A Receptor:6.5 nM (IC50, rat)"},{name: "5-HT1A Receptor:0.1 nM (IC50, human)"},{name: "rD2 Receptor:15.1 nM (IC50, rat)"},{name: "D3 Receptor:6.8 nM (IC50, human)"},{name: "5-HT1B Receptor:600 nM (IC50, rat)"},{name: "5-HT1D Receptor:500 nM (IC50, calf)"},{name: "5-HT2A Receptor:960 nM (IC50, rat, agonist site)"},{name: "5-HT2A Receptor:587 nM (IC50, human, antagonist site)"},{name: "5-HT2B Receptor:108 nM (IC50, human)"},{name: "5-HT2C Receptor:800 nM (IC50, pig)"},{name: "5-HT3 Receptor:3500 nM (IC50, NG 108 cells)"},{name: "5-HT5A Receptor:313 nM (IC50, human)"},{name: "5-HT6 Receptor:3300 nM (IC50, human)"},{name: "5-HT7 Receptor:10 nM (IC50, human)"},{name: "hD4.2 Receptor:2.4 nM (IC50)"},{name: "hD2 Receptor:17 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
