Rolapitant hydrochloride hydrate
Cat. No.：YN322803
| 产品名称: | Rolapitant hydrochloride hydrate |
| CAS No.: | 914462-92-3 |
| Chemical Name: | |
| Synonyms: | SCH619734 hydrochloride hydrate |
| 分子量: | 暂无 |
| 分子式: | 暂无 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) 是一种长效且具有选择性和口服活性的神经激肽 1 (NK1) 受体拮抗剂，Ki值为 0.66 nM。Rolapitant hydrochloride hydrate 不与 CYP3A4 产生互作。Rolapitant hydrochloride hydrate 在雪貂呕吐模型中显示出强效的止吐活性。 |
| IC50和靶点: | [{name:"human NK1:0.66 nM (Ki)"},{name: "gerbil NK1:0.13 nM (Ki)"},{name: "guinea pig NK1:0.72 nM (Ki)"},{name: "monkey NK1:2.5 nM (Ki)"},{name: "rabbit NK1:31.7 nM (Ki)"},{name: "rat NK1:78.6 nM (Ki)"},{name: "mouse NK1:60.4 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
