Saterinone
Cat. No.：YN380467
CAS No. ：102669-89-6
| 产品名称: | Saterinone |
| CAS No.: | 102669-89-6 |
| Chemical Name: | 1,2-Dihydro-5-[4-[2-hydroxy-3-[4-(2-methoxyphenyl)-1-piperazinyl]propoxy]phenyl]-6-methyl-2-oxo-3-pyridinecarbonitrile; BDF 8634; |
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| 分子量: | 441.35 |
| 分子式: | C21H26Cl2N2O4 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Saterinone 是一种强效且具有选择性的磷酸二酯酶III抑制剂，是血管α - 1-肾上腺素受体的有效拮抗剂。Saterinone具有血管舒张作用，可用于慢性心力衰竭的急性治疗。Saterinone 对豚鼠右心室匀浆中粗cAMP磷酸二酯酶(PDE)活性具有抑制作用，ic50值为2.3 × 10(-5) mol/l。 |
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Schmitz, W., et al.: Basic Res. Cardiol., 87, 65 (1992)
Thompson, P., et al.: Curr. Top. Med. Chem., 7, 421 (2007)
