Donitriptan hydrochloride
Cat. No.:YN380521
CAS No. :170911-68-9
产品名称: | Donitriptan hydrochloride |
CAS No.: | 170911-68-9 |
Chemical Name: | 4-[4-[2-[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]benzonitrile Hydrochloride; 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)piperazine Hydrochloride; F 11356; |
Synonyms: | Donitriptan HCl,盐酸多尼普曲坦,Donitriptan monohydrochloride |
分子量: | 439.94 |
分子式: | C23H26ClN5O2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Donitriptan hydrochloride 是一种有效的高亲和力 5-HT1B/1D 受体激动剂,pKi 分别为 9.4 和 9.3。 |
IC50和靶点: | |
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Solvent & Solubility: |
Pauwels, P., et al.: Biochem. Pharmacol., 46, 535 (1993), Kleven, M., et al.: Eur. J. Pharmacol., 281, 219 (1995), Perez, M., et al.: J. Med. Chem., 38, 3602 (1995), Le Grand, B., et al.: J. Cardiovasc. Pharmacol., 32, 435 (1998),