Nelivaptan
Cat. No.：YN322899
| 产品名称: | Nelivaptan |
| CAS No.: | 439687-69-1 |
| Chemical Name: | (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide; Nelivaptan |
| Synonyms: | SSR-149415 |
| 分子量: | 630.10838 |
| 分子式: | C30H32N3O8Scl |
| SMILES: | CN(C)C(=O)[C@@H]1C[C@H](CN1[C@@]2(C3=CC=CC=C3OC)C4=C(C=CC(=C4)Cl)N(C2=O)S(=O)(=O)C5=C(C=C(C=C5)OC)OC)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nelivaptan (SSR-149415) 是一种选择性的具有口服活性的vasopressin V1b Receptor拮抗剂 (对天然和重组大鼠 V1b 受体的Ki值分别为 3.7 和 1.3 nM)。Nelivaptan 抑制精氨酸加压素 (AVP) 诱导的 Ca2+增加和促肾上腺皮质激素分泌。Nelivaptan 可用于压力和焦虑的研究。 |
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| Solvent & Solubility: |
Greibel, G.
et al.: Proc. Nat. Acad. Sci. U.S.A., 99, 6370 (2002)
