Muscarine iodide
Cat. No.:YN322903
产品名称: | Muscarine iodide |
CAS No.: | 50-10-2 |
Chemical Name: | 2-[(2-cyclohexyl-2-hydroxy-2-phenylacetyl)oxy]-N,N-diethyl-N-methyl-ethanaminium, monobromide |
Synonyms: | |
分子量: | 428.4 |
分子式: | C21H34NO3 • Br |
SMILES: | CC[N+](CCOC(C(C1=CC=CC=C1)(O)C2CCCCC2)=O)(C)CC.[Br-] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Oxyphenonium bromide 是一种抗乙酰胆碱化合物。Oxyphenium bromide 是一种mAChR拮抗剂。Oxyphenonium bromide 可抵抗支气管阻塞效应。 |
IC50和靶点: | |
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Eglen, R.M., and Whiting, R.L.Competitive and non-competitive antagonism exhibited by 'selective' antagonists at atrial and ileal muscarinic receptor subtypesBr. J. Pharmacol.90(4),701-707(1987)
Wilimowski, M., Orzechowska, K., Prandota, J., et al.Comparative quantitative studies on cholinolytics. 3. The action of propanteline, methanteline, oxyphenonium and diphemanilArch. Immunol. Ther. Exp. (Warsz.)18(1),139-142(1970)
Barrett, W.E., Rutledge, R., Plummer, A.J., et al.Inhibition of ulcer formation in the Shay rat and reduction of gastric acidity in dogs by antrenyl (oxyphenonium) (BA5473) diethyl(2-hydroxyethyl)methylammonium bromide α-phenyl-cyclohexaneglycolate, an anticholinergic agentJ. Pharmacol. Exp. Ther.108(3),305-316(1953)
Luft, W.A., Ming, Y., and Stell, W.K.Variable effects of previously untested muscarinic receptor antagonists on experimental myopiaInvest. Ophthalmol. Vis. Sci.44(3),1330-1338(2003)