RPR121056
Cat. No.：YN380009
| 产品名称: | RPR121056 |
| CAS No.: | 181467-56-1 |
| Chemical Name: | 4-[(4-Carboxybutyl)amino]-1-piperidinecarboxylic Acid (4S)-4,11-Diethyl |
| Synonyms: | APC |
| 分子量: | 618.68 |
| 分子式: | C₃₃H₃₈N₄O₈ |
| SMILES: | O=C(N1CCC(NCCCCC(O)=O)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RPR121056 (APC) 是通过 CYP3A4 产生的 Irinotecan (CPT-11) 的代谢产物。Irinotecan (CPT-11) 是一种抗肿瘤药，可抑制 I 型拓扑异构酶 (topoisomerase type I)，引起细胞死亡，并用于大肠癌的研究。Irinotecan 也能直接抑制AChE。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996),
