Rivastigmine
Cat. No.：YN380119
CAS No. ：123441-03-2
| 产品名称: | Rivastigmine |
| CAS No.: | 123441-03-2 |
| Chemical Name: | Ethylmethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester; Ethylmethylcarbamic Acid 3-[1-(dimethylamino)ethyl]phenyl Ester, (S)-; ENA 713 Free Base; Exelon; Rivastigmine; S-Rivastigmine; SDZ 212-713; |
| Synonyms: | 卡巴拉汀; S |
| 分子量: | 250.34 |
| 分子式: | C₁₄H₂₂N₂O₂ |
| SMILES: | O=C(N(C)CC)OC1=CC=CC([C@H](C)N(C)C)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rivastigmine (S-Rivastigmine) 是一种具有口服活性的，有效的胆碱酯酶 (ChE) 抑制剂，可抑制丁酰胆碱酯酶 (BChE) 和乙酰胆碱酯酶 (AChE)，IC50分别为 0.037 μM 和 4.15 μM。Rivastigmine 可透过血脑屏障 (BBB)。Rivastigmine 是一种拟副交感神经剂或胆碱能剂，用于研究轻度至中度阿尔茨海默氏型痴呆和帕金森氏病引起的痴呆。 |
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| Solvent & Solubility: |
Howes, L et al.: Drug. Safe., 37, 391 (2014)
Shahar, O. et al.: Nucl. Acids Res., 42, 5869 (2014)
