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Linarin

Cat. No.:YN380230

  • CAS No. :480-36-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Linarin
      CAS No.: 480-36-4
      Chemical Name: 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:蒙花苷; Buddleoside;
      分子量:592.55
      分子式:C₂₈H₃₂O₁₄
      SMILES:O=C(C=C(C1=CC=C(OC)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO[C@H](O[C@@H](C)[C@H](O)[C@H]4O)[C@@H]4O)=C5)C2=C5O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Linarin (Buddleoside) 是从薄荷花提取物中分离得到的,选择性的抑制乙酰胆碱酯酶 (AChE)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Xu, Z.-F., Sun, X.-K., Lan, Y., et al.Linarin sensitizes tumor necrosis factor-related apoptosis (TRAIL)-induced ligand-triggered apoptosis in human glioma cells and in xenograft nude miceBiomed. Pharmacother.95,1607-1618(2017)

      Han, X., Wu, Y.-C., Meng, M., et al.Linarin prevents LPS‑induced acute lung injury by suppressing oxidative stress and inflammation via inhibition of TXNIP/NLRP3 and NF‑κB pathwaysInt. J. Mol. Med.42(3),1460-1472(2018)

      Pan, H., Zhang, J., Wang, Y., et al.Linarin improves the dyskinesia recovery in Alzheimer's disease zebrafish by inhibiting the acetylcholinesterase activity.Life Sci.222,112-116(2019)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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