Tenuifolin
Cat. No.：YN380234
| 产品名称: | Tenuifolin |
| CAS No.: | 20183-47-5 |
| Chemical Name: | (4α)-3β-(β-D-glucopyranosyloxy)-2β,27-dihydroxy-olean-12-ene-23,28-dioic acid |
| Synonyms: | 细叶远志皂苷 |
| 分子量: | 680.82 |
| 分子式: | C₃₆H₅₆O₁₂ |
| SMILES: | OC[C@@]1(CC[C@]2(C(O)=O)[C@@]3([H])CC(C)(C)CC2)C3=CC[C@@]4([H])[C@]1(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)[C@@]5(C)C(O)=O)C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tenuifolin 是从远志中分离出的三萜，具有神经保护作用。Tenuifolin 通过抑制β-secretase减少 Aβ 蛋白分泌。 Tenuifolin 可通过降低AChE活性来改善衰老小鼠的学习和记忆能力，有潜力用于阿尔茨海默氏病 (AD) 的研究。 |
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Liu, Y.-m., Li, Z.-y., Hu, H., et al.Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivoPharmacol. Biochem. Behav.128,14-22(2015)
Lv, J., Jiang, Y., Ruan, Y., et al.Tenuifolin, an extract derived from tenuigenin, inhibits amyloid-β secretion in vitroActa Physiol. (Oxf.)196(4),419-425(2009)
