Pteryxin
Cat. No.：YN380245
| 产品名称: | Pteryxin |
| CAS No.: | 13161-75-6 |
| Chemical Name: | (2Z)-2-methyl-2-butenoic acid, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b′]dipyran-10-yl ester |
| Synonyms: | 北美芹素; (+) |
| 分子量: | 386.40 |
| 分子式: | C₂₁H₂₂O₇ |
| SMILES: | C/C=C(C)\C(O[C@@H]1C2=C3C(C=CC(O3)=O)=CC=C2OC(C)(C)[C@@H]1OC(C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pteryxin，白花前胡叶中的香豆素，具有抗肥胖作用。Pteryxin 是一种有效的丁酰胆碱酯酶(BChE)抑制剂，IC50的值为 12.96 μg/ml。 |
| IC50和靶点: | |
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Matsuda, H., Murakami, T., Kageura, T., et al.Hepatoprotective and nitric oxide production inhibitory activities of coumarin and polyacetylene constituents from the roots of Angelica furcijugaBioorg. Med. Chem. Lett.8(16),2191-2196(1998)
Chen, I.-S., Chang, C.-T., Sheen, W.-S., et al.Coumarins and antiplatelet aggregation constituents from formosan Peucedanum japonicumPhytochemistry41(2),525-530(1996)
Orhan, I.E., Senol, F.S., Shekfeh, S., et al.Pteryxin - A promising butyrylcholinesterase-inhibiting coumarin derivative from Mutellina purpureaFood Chem. Toxicol.109(Pt 2),970-974(2017)
Nugara, R.N., Inafuku, M., Takara, K., et al.Pteryxin: A coumarin in Peucedanum japonicum Thunb leaves exerts antiobesity activity through modulation of adipogenic gene networkNutrition30(10),1177-1184(2014)
