Galanthamine N-Oxide
Cat. No.：YN380273
| 产品名称: | Galanthamine N-Oxide |
| CAS No.: | 134332-50-6 |
| Chemical Name: | (4aS,6R,8aS,11R)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 11-oxide |
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| 分子量: | 303.35 |
| 分子式: | C₁₇H₂₁NO₄ |
| SMILES: | O[C@H]1C=C[C@@]23CC[N@@+](C)([O-])CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Galanthamine N-Oxide 是一种生物碱，分离于Zephyranthes concolor的球茎中。Galanthamine N-Oxide 抑制电鳗乙酰胆碱酯酶 (AChE)，EC50为 26.2 μM。Galanthamine N-Oxide 是TcAChE，hAChE 和 hBChE 酶活性位点中底物调节的显著抑制剂。 |
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Mannens, G.S.J., Snel, C.A.W., Hendrickx, J., et al.The metabolism and excretion of galantamine in rats, dogs, and humansDrug Metab. Dispos.30(5),553-563(2002)
Reyes-Chilpa, R., Berkov, S., Hernández-Ortega, S., et al.Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolorMolecules16(11),9520-9533(2011)
Li, X., Yu, H.-Y., Wang, Z.-Y., et al.Neuroprotective compounds from the bulbs of Lycoris radiataFitoterapia88,82-90(2013)
