TGFβRI-IN-2
Cat. No.:YN440218
产品名称: | TGFβRI-IN-2 |
CAS No.: | 1976038-41-1 |
Chemical Name: | |
Synonyms: | TGFβRI-IN-2 |
分子量: | 411.82 |
分子式: | C₂₀H₁₅ClFN₅O₂ |
SMILES: | O=C(N)CN(C1=C2C=CN=C1)C(N2C3=CC(C4=CC(Cl)=CC=C4F)=NC=C3C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TGFβRI-IN-2 (compound 18) 是一种有效的,选择性的和口服活性的激活素样激酶 5 (ALK 5) 抑制剂,pIC50和pEC50值分别为 7.6 和 6.63。TGFβRI-IN-2 在高剂量时会在体内产生心脏毒性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |