Etretinate
Cat. No.:YN270427
CAS No. :54350-48-0
产品名称: | Etretinate |
CAS No.: | 54350-48-0 |
Chemical Name: | (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, ethyl ester |
Synonyms: | 依曲替酯; Ro 10-9359 |
分子量: | 354.48 |
分子式: | C₂₃H₃₀O₃ |
SMILES: | O=C(OCC)/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C=C(OC)C(C)=C1C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Etretinate (Ro 10-9359) 可用于银屑病的研究。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Hopkins, R., Bird, H.A., Jones, H., et al.A double-blind controlled trial of etretinate (Tigason) and ibuprofen in psoriatic arthritisAnn. Rheum. Dis.44(3),189-193(1985)
Turton, J.A., Williars, G.B., Haselden, J.N., et al.Comparative teratogenicity of nine retinoids in the ratInt. J. Exp. Path.73(5),551-563(1992)
Isuka, H., Ohkuma, N., and Ohkawara, A.Effects of retinoids on the cyclic AMP system of pig skin epidermisJ. Invest. Dermatol.85(4),324-327(1985)
Schopf, R.E., Langendorf, Y., Benz, R.E., et al.A highly decreased binding of cyclic adenosine monophosphate to protein kinase A in erythrocyte membranes is specific for active psoriasisJ. Invest. Dermatol.119(1),160-165(2002)