(S)-Ceralasertib
Cat. No.：YN420260
CAS No. ：1352226-87-9
| 产品名称: | (S)-Ceralasertib |
| CAS No.: | 1352226-87-9 |
| Chemical Name: | |
| Synonyms: | (S)-AZD6738 |
| 分子量: | 412.51 |
| 分子式: | C₂₀H₂₄N₆O₂S |
| SMILES: | O=[S@](C1(CC1)C2=NC(C3=C4C(NC=C4)=NC=C3)=NC(N5CCOC[C@H]5C)=C2)(C)=N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (S)-Ceralasertib ((S)-AZD6738) 从专利 WO2011154737A1 中获取，化合物 II，IC50为 2.578 nM。 (S)-Ceralasertib 是一种有效的选择性亚砜亚胺吗啉代嘧啶ATR抑制剂，具有优异的临床前物化和药代动力学 (PK) 特征。 (S)-Ceralasertib 水溶性改善，并且消除 CYP3A4 时间依赖性抑制。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
