AZD1390
Cat. No.：YN420065
CAS No. ：2089288-03-7
规格
价格(RMB)
库存
| 产品名称: | AZD1390 |
| CAS No.: | 2089288-03-7 |
| Chemical Name: | 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one |
| Synonyms: | |
| 分子量: | 477.57 |
| 分子式: | C₂₇H₃₂FN₅O₂ |
| SMILES: | O=C(N1C(C)C)N(C)C2=C1C3=CC(C4=CC=C(OCCCN5CCCCC5)N=C4)=C(F)C=C3N=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD1390 是一种有效的，高度选择性的，口服生物利用的，可渗透脑的ATM抑制剂，在细胞中对 ATM 的IC50为 0.78 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Durant, S.T., Zheng, L., Wang, Y., et al.The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor modelsSci. Adv.4(6),eaat1719(2018)
