CP-466722
Cat. No.：YN420066
CAS No. ：1080622-86-1
规格
价格(RMB)
库存
| 产品名称: | CP-466722 |
| CAS No.: | 1080622-86-1 |
| Chemical Name: | 1-(6,7-dimethoxy-4-quinazolinyl)-3-(2-pyridinyl)-1H-1,2,4-triazol-5-amine |
| Synonyms: | CP466722,CP 466722 |
| 分子量: | 349.35 |
| 分子式: | C₁₇H₁₅N₇O₂ |
| SMILES: | NC1=NC(C2=NC=CC=C2)=NN1C3=C4C=C(OC)C(OC)=CC4=NC=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CP-466722 是一种可逆的ATM抑制剂，IC50值为 4.1 μM，但对 PI3K，PIKK 家族蛋白没有作用。 |
| IC50和靶点: | [{name:"ATM:4.1 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Rainey, M.D., Charlton, M.E., Stanton, R.V., et al.Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiationCancer Res.68(18),7466-7474(2008)
