ATR inhibitor 2
Cat. No.：YN420176
CAS No. ：1613191-99-3
规格
价格(RMB)
库存
| 产品名称: | ATR inhibitor 2 |
| CAS No.: | 1613191-99-3 |
| Chemical Name: | |
| Synonyms: | ATR inhibitor 2 |
| 分子量: | 541.55 |
| 分子式: | C₂₅H₂₉F₂N₉O₃ |
| SMILES: | O=C(C1=C2N=CC(F)=CN2N=C1N)NC3=C(N4CCC(C(N5CCN(C6COC6)CC5)=O)CC4)C(F)=CN=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ATR inhibitor 2 是一种 ATP 竞争性的，具有口服活性的，选择性的ATR抑制剂，Ki<150 pM。ATR inhibitor 2 抑制 ATR 驱动的磷酸化检查点激酶-1 (Chk1) 磷酸化, IC50值为 8 nM。具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"ATR:<150 pM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
