CPI-444
Cat. No.：YN1440003
CAS No. ：1202402-40-1
| 产品名称: | CPI-444 |
| CAS No.: | 1202402-40-1 |
| Chemical Name: | 7-(5-methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine |
| Synonyms: | V81444; ciforadenant |
| 分子量: | 407.43 |
| 分子式: | C₂₀H₂₁N₇O₃ |
| SMILES: | NC1=NC(C2=CC=C(C)O2)=C(N=NN3CC4=NC(CO[C@@H]5COCC5)=CC=C4)C3=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CPI-444 (V81444) 是一种有效的选择性的，具有口服活性的 A2A 受体 (A2AR) 拮抗剂，可诱导抗肿瘤反应。 |
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| Solvent & Solubility: |
Scott, B.A., Armstrong, T., and Jaffee, E.M.Inhibition of adenosine A2A receptor (A2AR) by CPI-444 enhances CD8+ T cell killing of a HER-2/neu expressing murine tumorCancer Res.74(14),320(2016)
