Namodenoson
Cat. No.：YN1440047
CAS No. ：163042-96-4
| 产品名称: | Namodenoson |
| CAS No.: | 163042-96-4 |
| Chemical Name: | 1-[2-chloro-6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide |
| Synonyms: | CF-102; 2-Cl-IB-MECA |
| 分子量: | 544.73 |
| 分子式: | C₁₈H₁₈ClIN₆O₄ |
| SMILES: | O[C@H]([C@@H]1O)[C@@H](O[C@@H]1C(NC)=O)N2C3=NC(Cl)=NC(NCC4=CC(I)=CC=C4)=C3N=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Namodenoson (CF-102) 是一个选择性的 A3 腺苷受体 (A3AR) 激动剂 (Ki=0.33 nM)，选择性分别是 A1，A2 的 2500 和 1400 倍。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kim, H.O., Ji, X.d., Siddiqi, S.M., et al.2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptorsJ. Med. Chem.37(21),3614-3621(1994)
Fishman, P., Bar-Yehuda, S., Barer, F., et al.The A3 adenosine receptor as a new target for cancer therapy and chemoprotectionExp. Cell Res.269(2),230-236(2001)
