SCH 58261
Cat. No.：YN1441162
CAS No. ：160098-96-4
| 产品名称: | SCH 58261 |
| CAS No.: | 160098-96-4 |
| Chemical Name: | 2-(2-furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine |
| Synonyms: | SCH58261 |
| 分子量: | 345.36 |
| 分子式: | C₁₈H₁₅N₇O |
| SMILES: | NC1=NC(N(CCC2=CC=CC=C2)N=C3)=C3C4=NC(C5=CC=CO5)=NN14 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SCH 58261 是一种强效、选择性的竞争性腺苷 A2A 受体拮抗剂，IC50值为 15 nM，对 A2A 受体的选择性分别是 A1、A2B 和 A3 受体的 323 倍、53 倍、100 倍。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zocchi, C., Ongini, E., Ferrara, S., et al.Binding of the radioligand [3H]-SCH 58261, a new non-xanthine A2A adenosine receptor antagonist, to rat striatal membranesBr. J. Pharmacol.117(7),1381-1386(1996)
Reyhani-Rad, S., and Mahmoudi, J.Effect of adenosine A2A receptor antagonists on motor disorders induced by 6-hydroxydopamine in ratActa Cir. Bras.31(2),133-137(2016)
