MRS-1706
Cat. No.：YN1710006
CAS No. ：264622-53-9
| 产品名称: | MRS-1706 |
| CAS No.: | 264622-53-9 |
| Chemical Name: | N-(4-acetylphenyl)-2-[4-(2,3,6,9-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide |
| Synonyms: | MRS-1706,MRS 1706,MRS1706 |
| 分子量: | 503.55 |
| 分子式: | C₂₇H₂₉N₅O₅ |
| SMILES: | O=C(NC1=CC=C(C(C)=O)C=C1)COC2=CC=C(C3=NC(N(CCC)C(N(CCC)C4=O)=O)=C4N3)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MRS-1706 是一种有效选择的A2B腺苷受体的反向激动剂。MRS-1706 对人 A2B、A2A、A1和 A3受体的Ki值分别为 1.39、112、157 和 230 nM。 |
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Kim, Y.-C., Ji, X.-d., Melman, N., et al.Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A2B adenosine receptorsJ. Med. Chem.43(6),1165-1172(2000)
Li, Q., Ye, K., Blad, C.C., et al.ZM241385, DPCPX, MRS1706 are inverse agonists with different relative intrinsic efficacies on constitutively active mutants of the human adenosine A2B receptorJ. Pharmacol. Exp. Ther.320(2),637-645(2007)
