Adenosine amine congener
Cat. No.：YN1710017
CAS No. ：96760-69-9
| 产品名称: | Adenosine amine congener |
| CAS No.: | 96760-69-9 |
| Chemical Name: | N-[4-[2-[[4-[2-[(2-aminoethyl)amino]-2-oxoethyl]phenyl]amino]-2-oxoethyl]phenyl]-adenosine |
| Synonyms: | ADAC |
| 分子量: | 576.60 |
| 分子式: | C₂₈H₃₂N₈O₆ |
| SMILES: | OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NC4=CC=C(CC(NC5=CC=C(CC(NCCN)=O)C=C5)=O)C=C4)O1)O)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Adenosine amine congener (ADAC) 是一种选择性的 A1 腺苷受体 (A1 adenosine receptor) 激动剂，可以改善噪音和顺铂引起的耳蜗损伤。Adenosine amine congener 还具有神经保护作用。 |
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Von Lubitz, D.K.J.E., Lin, R.C.-S., Bischofberger, N., et al.Protection against ischemic damage by adenosine amine congener, a potent and selective adenosine A1 receptor agonistEur. J. Pharmacol.369(3),313-317(1999)
Vlajkovic, S.M., Lee, K.-H., Wong, A.C.Y., et al.Adenosine amine congener mitigates noise-induced cochlear injuryPurinergic Signal.6(2),273-281(2010)
Karl, M.O., Fleischhauer, J.C., Stamer, W.D., et al.Differential P1-purinergic modulation of human Schlemm’s canal inner-wall cellsAm. J. Physiol. Cell Physiol.288(4),C784-C794(2005)
