Vipadenant
Cat. No.：YN1730027
| 产品名称: | Vipadenant |
| CAS No.: | 442908-10-3 |
| Chemical Name: | 3-[(4-amino-3-methylphenyl)methyl]-7-(2-furanyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine |
| Synonyms: | BIIB-014; CEB-4520 |
| 分子量: | 321.34 |
| 分子式: | C₁₆H₁₅N₇O |
| SMILES: | NC1=NC2=C(N=NN2CC3=CC=C(N)C(C)=C3)C(C4=CC=CO4)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vipadenant (BIIB-014; CEB-4520) 是腺苷受体拮抗剂，抑制 A2A 和 A1 活性的Ki值分别为 1.3 nM 和 68 nM。 |
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Gillespie, R.J., Bamford, S.J., Botting, R., et al.Antagonists of the human A2A adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo[4,5-d]pyrimidinesJ. Med. Chem.52(1),33-47(2009)
