AB-MECA
Cat. No.：YN1730083
| 产品名称: | AB-MECA |
| CAS No.: | 152918-26-8 |
| Chemical Name: | 1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-β-D-ribofuranuronamide |
| Synonyms: | b-D-Ribofuranuronamide,1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-;(2S,3S,4R,5R)-5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide;2,2'-((3-METHOXYPHENYL)AZANEDIYL)DIETHANOL;AB-MECA;(2S,3S,4R |
| 分子量: | 399.40 |
| 分子式: | C₁₈H₂₁N₇O₄ |
| SMILES: | O[C@H]1[C@H](N2C=NC3=C(NCC4=CC=C(N)C=C4)N=CN=C23)O[C@H](C(NC)=O)[C@H]1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AB-MECA是一种高亲和性A3腺苷受体激动剂, 对重组A1和A3受体具有高亲和性。 |
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Yates, L., Clark, J.H., Martin, T.J., et al.Radioligand binding and functional responses of ligands for human recombinant adenosine A3 receptorsAuton. Autacoid Pharmacol.26(2),191-200(2006)
Buenestado, A., Grassin Delyle, S., Arnould, I., et al.The role of adenosine receptors in regulating production of tumour necrosis factor-α and chemokines by human lung macrophagesBr. J. Pharmacol.159(6),1304-1311(2010)
Mikus, E.G., Szeredi, J., Boer, K., et al.Evaluation of SSR161421, a novel orally active adenosine A3 receptor antagonist on pharmacology modelsEur. J. Pharmacol.699(1-3),172-179(2013)
Olah, M.E., Gallo-Rodriguez, C., Jacobson, K.A., et al.125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptorMol. Pharmacol.45(5),978-982(1994)
