SQ22536
Cat. No.:YN320039
CAS No. :17318-31-9
产品名称: | SQ22536 |
CAS No.: | 17318-31-9 |
Chemical Name: | 9-(tetrahydro-2-furanyl)-9H-purin-6-amine |
Synonyms: | 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine |
分子量: | 205.22 |
分子式: | C₉H₁₁N₅O |
SMILES: | NC1=C2N=CN(C3OCCC3)C2=NC=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SQ22536 是一种有效的腺苷酸环化酶 (AC) 抑制剂。 |
IC50和靶点: | |
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Haslam, R.J., Davidson, M.M.L., and Desjardins, J.V.Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human plateletsBiochem. J.176(1),83-95(1978)
Turcato, S., and Clapp, L.H.Effects of the adenylyl cyclase inhibitor SQ22536 on iloprost-induced vasorelaxation and cyclic AMP elevation in isolated guinea-pig aortaBr. J. Pharmacol.126(4),845-847(1999)
Gao, Y., and Raj, J.U.Effects of SQ 22536, an adenylyl cyclase inhibitor, on isoproterenol-induced cyclic AMP elevation and relaxation in newborn ovine pulmonary veinsEur. J. Pharmacol.436(3),227-233(2002)