NKY80
Cat. No.：YN320246
CAS No. ：299442-43-6
| 产品名称: | NKY80 |
| CAS No.: | 299442-43-6 |
| Chemical Name: | 2-amino-7-(2-furanyl)-7,9-dihydro-5(6H)-quinazolinone |
| Synonyms: | Adenylyl cyclase type V Inhibitor |
| 分子量: | 229.23 |
| 分子式: | C₁₂H₁₁N₃O₂ |
| SMILES: | O=C1C2=CN=C(N)N=C2CC(C3=CC=CO3)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | NKY80 是一种有效的，选择性和非竞争性的 V 型腺苷酸环化酶 (AC) 异构体抑制剂，对于 V 型，III 型和 II 型，IC50分别为 8.3 µM，132 µM 和 1.7 mM。NKY80 是一种非核苷的喹唑啉酮，可调节心脏和肺组织中的 AC 催化活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Onda, T., Hashimoto, Y., Nagai, M., et al.Type-specific regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoformsJ. Biol. Chem.276(51),47785-27793(2001)
