Gramine
Cat. No.:YN321713
产品名称: | Gramine |
CAS No.: | 87-52-5 |
Chemical Name: | N,N-dimethyl-1H-indole-3-methanamine |
Synonyms: | Donaxine |
分子量: | 174.24 |
分子式: | C₁₁H₁₄N₂ |
SMILES: | CN(C)CC1=CNC2=C1C=CC=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Gramine (Donaxine) 是从芦竹中得到的生物碱,为有效的脂联素受体 (adiponectin receptor (AdipoR)) 激动剂,对 AdipoR2 和 AdipoR1 的IC50值分别为 3.2 和 4.2 µM。Gramine 同时为小鼠和人β2-Adrenergic receptor (β2-AR)激动剂。Gramine 具有抗肿瘤、抗炎和抗病毒作用。 |
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Froldi, G., Silvestrin, B., Dorigo, P., et al.Gramine: A vasorelaxing alkaloid acting on 5-HT2A receptorsPlanta Med.70(4),373-375(2004)