Hydroxybupropion
Cat. No.:YN320065
产品名称: | Hydroxybupropion |
CAS No.: | 92264-81-8 |
Chemical Name: | |
Synonyms: | Hydroxybupropione,6-Hydroxybupropion,Hydroxybupropion, (+/-)- |
分子量: | 255.74 |
分子式: | C₁₃H₁₈ClNO₂ |
SMILES: | CC(NC(C)(C)CO)C(C1=CC=CC(Cl)=C1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Hydroxybupropion 是 Bupropion 的主要活性代谢产物。Hydroxybupropion 是通过 CYP2B6 代谢的。Bupropion 是一种非典型的抗抑郁药和戒烟药。Hydroxybupropion 抑制去甲肾上腺素的摄取,IC50值为 1.7 μM。Hydroxybupropion 也是nACh受体拮抗药,比 Bupropion 更有效。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
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