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BRL 37344 sodium

Cat. No.:YN320128

  • CAS No. :127299-93-8

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    • 产品名称: BRL 37344 sodium
      CAS No.: 127299-93-8
      Chemical Name: rel-2-[4-[(2S)-2-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]phenoxy]-acetic acid, monosodium salt
      Synonyms:BRL 37344A
      分子量:385.82
      分子式:C₁₉H₂₁ClNNaO₄
      SMILES:O=C(O[Na])COC1=CC=C(C[C@@H](NC[C@H](C2=CC=CC(Cl)=C2)O)C)C=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: BRL 37344 sodium (BRL 37344A) 是特异性β3-肾上腺素能受体 (β3-adrenergic receptor)激动剂。 BRL 37344 sodium 显著降低了肥胖小鼠的体重。
      IC50和靶点:
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    • Hoffmann, C., Leitz, M.R., Oberdorf-Maass, S., et al.Comparative pharmacology of human β-adrenergic receptor subtypes—characterization of stably transfected receptors in CHO cellsN.-S. Arch. Pharmacol.369(2),151-159(2004)

      Kanzler, S.A., Januario, A.C., and Paschoalini, M.A.Involvement of β3-adrenergic receptors in the control of food intake in ratsBraz. J. Med. Biol. Res.44(11),1141-1147(2011)

      Niu, X., Zhao, L., Li, X., et al.β3-Adrenoreceptor stimulation protects against myocardial infarction injury via eNOS and nNOS activationPLoS One9(6),(2014)

      Butler, T.R., Chappell, A.M., and Weiner, J.L.Effect of β3 adrenoceptor activation in the basolateral amygdala on ethanol seeking behaviorsPsychoph. S.231(1),293-303(2014)

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