Piribedil
Cat. No.：YN320630
CAS No. ：3605-01-4
| 产品名称: | Piribedil |
| CAS No.: | 3605-01-4 |
| Chemical Name: | 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-pyrimidine |
| Synonyms: | Trivastal, Trivastan |
| 分子量: | 298.34 |
| 分子式: | C₁₆H₁₈N₄O₂ |
| SMILES: | C1(N2CCN(CC3=CC=C(OCO4)C4=C3)CC2)=NC=CC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Piribedil 是一种多巴胺 D2受体 (D2R) 激动剂，对 hα1A-肾上腺素受体 (hα1A-AR) 也显示出拮抗作用。 |
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Cagnotto, A., Parotti, L., and Mennini, T.In vitro affinity of piribedil for dopamine D3 receptor subtypes, an autoradiographic studyEur. J. Pharmacol.313(1-2),63-67(1996)
Marighetto, A., Valerio, S., Philippin, J.N., et al.Comparative effects of the dopaminergic agonists piribedil and bromocriptine in three different memory paradigms in rodentsJ. Psychopharmacol.22(5),511-521(2008)
Brocco, M., Dekeyne, A., Papp, M., et al.Antidepressant-like properties of the anti-Parkinson agent, piribedil, in rodents: Mediation by dopamine D2 receptorsBehav. Pharmacol.17(7),559-572(2006)
Turle-Lorenzo, N., Maurin, B., Puma, C., et al.The dopamine agonist piribedil with L-DOPA improves attentional dysfunction: Relevance for Parkinson's diseaseJ. Pharmacol. Exp. Ther.319(2),914-923(2006)
