Vilanterol
Cat. No.:YN320846
CAS No. :503068-34-6
产品名称: | Vilanterol |
CAS No.: | 503068-34-6 |
Chemical Name: | α1R-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-1,3-benzenedimethanol |
Synonyms: | 维兰特罗; GW642444 |
分子量: | 486.43 |
分子式: | C₂₄H₃₃Cl₂NO₅ |
SMILES: | OC1=CC=C([C@@H](O)CNCCCCCCOCCOCC2=C(Cl)C=CC=C2Cl)C=C1CO |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Vilanterol (GW642444) 是一种长效的β2-AR激动剂,效力持续24小时。 对β2-AR,β1-AR和β3-AR的pEC50分别为10.37,6.98 ,7.36。 |
IC50和靶点: | |
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Procopiou, P.A., Barrett, V.J., Bevan, N.J., et al.Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating metabolic inactivation: An antedrug approachJ. Med. Chem.53(11),4522-4530(2010)