Metipranolol hydrochloride
Cat. No.：YN321058
CAS No. ：36592-77-5
| 产品名称: | Metipranolol hydrochloride |
| CAS No.: | 36592-77-5 |
| Chemical Name: | 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2,3,6-trimethyl-phenol, 1-acetate, monohydrochloride |
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| 分子量: | 345.86 |
| 分子式: | C₁₇H₂₈ClNO₄ |
| SMILES: | CC1=C(OC(C)=O)C(C)=C(C)C(OCC(O)CNC(C)C)=C1.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Metipranolol hydrochloride 是一种非选择性的 β 肾上腺素受体 (β adrenergic receptor) 阻断剂。可用于肺动脉高压及用于青光眼的研究。 |
| IC50和靶点: | |
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Sugrue, M.F., Armstrong, J.M., Gautheron, P.D., et al.A study on the ocular and extraocular pharmacology of metipranololGraefes. Arch. Clin. Exp. Ophthalmol.222(3),123-127(1985)
Wood, J.P.M., Schmidt, K.-G., Melena, J., et al.The β-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: Comparison with betaxololExp. Eye Res.76(4),505-516(2003)
Osborne, N.N., and Wood, J.P.M.Metipranolol blunts nitric oxide-induced lipid peroxidation and death of retinal photoreceptors: A comparison with other anti-glaucoma drugsInvest. Ophthalmol. Vis. Sci.45(10),3787-3795(2004)
