Dexmedetomidine hydrochloride
Cat. No.:YN321105
产品名称: | Dexmedetomidine hydrochloride |
CAS No.: | 145108-58-3 |
Chemical Name: | 5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride |
Synonyms: | 盐酸右美托咪定; (+)-Medetomidine hydrochloride; (S)-Medetomidine hydrochloride |
分子量: | 236.74 |
分子式: | C₁₃H₁₇ClN₂ |
SMILES: | C[C@H](C1=CN=CN1)C2=CC=CC(C)=C2C.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Dexmedetomidine Hydrochloride 是α2肾上腺素受体激动剂,有止痛镇静活性。 |
IC50和靶点: | [{name:"α2-adrenergic receptor:1.08 nM (IC50)"}] |
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Kuusela, E., Vainio, O., Kaistinen, A., et al.Sedative, analgesic, and cardiovascular effects of levomedetomidine alone and in combination with dexmedetomidine in dogsAm. J. Vet. Res.62(4),616-621(2001)
Gertler, R., Brown, H.C., Mitchell, C.H., et al.Dexmedetomidine: A novel sedative-analgesic agentProc. (Bayl. Univ. Med. Cent.)14(1),13-21(2001)
Meert, T.F., and de Kock, M.Potentiation of the analgesic properties of fentanyl-like opioids with α2-adrenoceptor agonists in ratsAnesthesiology81(3),677-688(1994)