Atenolol
Cat. No.：YN321149
| 产品名称: | Atenolol |
| CAS No.: | 29122-68-7 |
| Chemical Name: | 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetamide |
| Synonyms: | 阿替洛尔; (RS) |
| 分子量: | 266.34 |
| 分子式: | C₁₄H₂₂N₂O₃ |
| SMILES: | O=C(N)CC1=CC=C(OCC(O)CNC(C)C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Atenolol ((RS)-Atenolol) 是一种心脏选择性的 β1 肾上腺素能受体 (β1-adrenergic receptor) 阻断剂。Atenolol 在豚鼠左心室膜β1肾上腺素能受体处的Ki为 697 nM。阿替洛尔可用于高血压和心绞痛的研究。 |
| IC50和靶点: | [{name:"Beta-1 adrenergic receptor:697 nM (Ki)"}] |
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Mehvar, R., and Brocks, D.R.Stereospecific pharmacokinetics and pharmacodynamics of β-adrenergic blockers in humansJ. Pharm. Pharm. Sci.4(2),185-200(2001)
Gupta, P., and Goyal, R.N.Amino functionalized graphene oxide and polymer nanocomposite based electrochemical platform for sensitive assay of anti-doping drug atenolol in biological fluidsJ. Electrochem. Soc.163(13),B601-B608(2016)
