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Bambuterol hydrochloride

Cat. No.:YN321151

  • CAS No. :81732-46-9

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    • 产品名称: Bambuterol hydrochloride
      CAS No.: 81732-46-9
      Chemical Name: N,N-dimethyl-carbamic acid-3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, monohydrochloride
      Synonyms:盐酸班布特罗; (±)
      分子量:403.90
      分子式:C₁₈H₃₀ClN₃O₅
      SMILES:OC(C1=CC(OC(N(C)C)=O)=CC(OC(N(C)C)=O)=C1)CNC(C)(C)C.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Bambuterol hydrochloride ((±)-Bambuterol hydrochloride; KWD-2183 hydrochloride) 是肾上腺素受体长效激动剂,Terbutaline的前体药物。
      IC50和靶点:
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      In Vivo:
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    • Fukami, T., and Yokoi, T.The emerging role of human esterasesDrug Metab. Pharmacokinet.27(5),466-477(2012)

      Hoffmann, C., Leitz, M.R., Oberdorf-Maass, S., et al.Comparative pharmacology of human β-adrenergic receptor subtypes—characterization of stably transfected receptors in CHO cellsN.-S. Arch. Pharmacol.369(2),151-159(2004)

      Pistolozzi, M., Du, H., Wei, H., et al.Stereoselective inhibition of human butyrylcholinesterase by the enantiomers of bambuterol and their intermediatesDrug Metab. Dispos.43(3),344-352(2015)

      Xie, Q.-M., Zeng, L.-H., Zheng, Y.-X., et al.Bronchodilating effects of bambuterol on bronchoconstriction in guinea pigsZhongguo Yao Li Xue Bao20(7),651-654(1999)

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