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Fenspiride Hydrochloride

Cat. No.:YN321334

  • CAS No. :5053-08-7

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    • 参考文献
    • 产品名称: Fenspiride Hydrochloride
      CAS No.: 5053-08-7
      Chemical Name: 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one, monohydrochloride
      Synonyms:Fenspiride HCl,Pneumorel,Fluiden,Decaspiride,盐酸芬司必利
      分子量:296.79
      分子式:C₁₅H₂₁ClN₂O₂
      SMILES:O=C1OC2(CCN(CCC3=CC=CC=C3)CC2)CN1.[H]Cl
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Fenspiride盐酸盐是肾上腺素能受体和H1受体拮抗剂。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Rognoni, F., Marchini, F., Piacenza, G., et al.Effect of 8-N-phenethyl-1-oxa-2-oxo-3,8-diazaspiro(4,5)decane hydrochloride (decaspiride) on histamine receptorsBoll. Chim. Farm.117(7),397-401(1978)

      Laude, E.A., Bee, D., Crambes, O., et al.Antitussive and antibronchoconstriction actions of fenspiride in guinea-pigsEur. Respir. J.8(10),1699-1704(1995)

      Cortijo, J., Naline, E., Ortiz, J.L., et al.Effects of fenspiride on human bronchial cyclic nucleotide phosphodiesterase isoenzymes: Functional and biochemical studyEur. J. Pharmacol.341(1),79-86(1998)

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