Tolazoline hydrochloride
Cat. No.:YN321339
产品名称: | Tolazoline hydrochloride |
CAS No.: | 59-97-2 |
Chemical Name: | 4,5-dihydro-2-(phenylmethyl)-1H-imidazole, monohydrochloride |
Synonyms: | Imidaline hydrochloride; NSC35110 hydrochloride |
分子量: | 196.68 |
分子式: | C₁₀H₁₃ClN₂ |
SMILES: | [H]Cl.C1(CC2=CC=CC=C2)=NCCN1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tolazoline(Imidaline)盐酸盐是_alpha_-肾上腺素受体抑制剂。 |
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Megens, A.A.H.P., Leysen, J.E., Awouters, F.H.L., et al.Further validation of in vivo and in vitro pharmacological procedures for assessing the ɑ2/ɑ1-selectivity of test compounds: (1) ɑ-adrenoceptor antagonistsEur. J. Pharmacol.129(1-2),49-55(1986)
Schwartz, D.D., and Clark, T.P.Selectivity of atipamezole, yohimbine and tolazoline for alpha-2 adrenergic receptor subtypes: Implications for clinical reversal of alpha-2 adrenergic receptor mediated sedation in sheepJ. Vet. Pharmacol. Ther.21(5),342-347(1998)
Costa, P., Soulie-Vassal, M.L., Sarrazin, B., et al.Adrenergic receptors on smooth muscle cells isolated from human penile corpus cavernosumJ. Urol.150(3),859-863(1993)
Rogers, R.A., and Riviere, J.E.Pharmacologic modulation of the cutaneous vasculature in the isolated perfused porcine skin flapJ. Pharm. Sci.83(12),1682-1689(1994)